Rethinking Genetic Links To Obesity: Irx3 Is Likely The ‘fat Gene’

The study appears online March 12 in Nature. “Our data strongly suggest that IRX3 controls body mass and regulates body composition,” said senior study author Marcelo Nobrega, PhD, associate professor of human genetics at the University of Chicago. “Any association between FTO and obesity appears due to the influence of IRX3.” Mutations to introns (noncoding portions) of the gene FTO have been widely investigated after genome-wide association studies revealed a strong link between FTO and obesity and diabetes. Yet overexpressing or deleting FTO in animal models affects whole body mass and composition, not just fat, and experiments have failed to show that these obesity-linked introns affect the function of the FTO gene itself. Hoping to explain these observations, Nobrega and his team mapped the behavior of promotersregions of DNA that activate gene expression located within one million base pairs on either side of the FTO gene.

Child obesity number drops statewide, but SFPS rate higher

The foods that fill kids up and are the least expensive are not necessarily the most nutritious, she said. Fruits and veggies cost more in the grocery stores. Its a struggle for families to give their children healthy foods, even if they want to. They may not be able to afford them. The Health Department released data Tuesday reflecting the change in obesity rates for both kindergartners and third-graders the only two grades it follows for its annual study, which it started in 2010. That report notes that while obesity levels for third-graders have dropped, kindergarten obesity levels across the state rose slightly, from 13.2 percent in 2010 to 13.7 percent in 2013. The obesity rate for kindergartners in Santa Fe is close to 20 percent, again higher than the state average.

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Prudential Financial Reschedules 2014 Financial Strength Symposium

Finance minister honors ANB for key Kafala role

For more information, please write to investor.relations@prudential.com . Prudential Financial, Inc. ( PRU ), a financial services leader with approximately $1.1 trillion of assets under management as of December 31, 2013, has operations in the United States, Asia, Europe and Latin America. Prudentials diverse and talented employees are committed to helping individual and institutional customers grow and protect their wealth through a variety of products and services, including life insurance, annuities, retirement-related services, mutual funds and investment management. In the U.S., Prudentials iconic Rock symbol has stood for strength, stability, expertise and innovation for more than a century.

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Army Suicides Linked Back To Pre-deployment Mental Health Woes

About 25 percent of soldiers had a mental health disorder before enlisting compared to 11.6 percent of the general population, Harvard researchers reported in the March 4 issue of JAMA Psychiatry . Eleven percent of Army soldiers likely met criteria for two mental health disorders prior to enlistment. “Some of the differences in disorder rates are truly remarkable,” study author Dr. Ronald Kessler, a health care policy researcher at Harvard Medical School in Boston, said in a statement . The study, along with two others published in the same journal issue, were part of the Army STARRS (Army Study to Assess Risk and Resilience in Service members).

Why Matthew McConaughey should win an Oscar for health

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The bad news is that the same study, based on national surveys, showed no significant changes in obesity rates in older children or in most adults. In fact, obesity rates went up among women 60 and older. A third of American adults and 17 percent of youths are obese. Clearly, there is a lot of work to do. The dietary and physical activity behaviors of children and adolescents are influenced by many sectors of society including families, communities, schools, child care settings, medical care providers, and the food and beverage industries and entertainment industries.

Discover Financial Faces Us Probe Over Student Lending

The CFPB had said in December it would start supervising the seven largest student loan servicers to ensure fair treatment to borrowers. The watchdog had pegged the student loan debt at $1.2 trillion. The company also disclosed that the Federal Deposit Insurance Corp (FDIC) has notified it of “potential deficiencies” in Discover Bank’s anti-money laundering program. The Bank Secrecy Act requires companies to assist government agencies detect and prevent money laundering. Discover Bank is cooperating with the agencies and enforcement action from either could include demands for civil money penalties, the company said.